Urticaria pigmentosa - Urtikarja Pigmentosa
Urtikarja Pigmentosa (Urticaria pigmentosa) hija l-aktar forma komuni ta' mastoċitożi tal-ġilda. Hija marda rari kkawżata minn numri eċċessivi ta 'ċelluli mast fil-ġilda li jipproduċu ħorriqija jew leżjonijiet fuq il-ġilda meta irritata. Tikek ħomor jew kannella spiss jidhru fuq il-ġilda, tipikament madwar is-sider, forehead, u dahar. Dawn iċ-ċelluli mast, meta jkunu irritati (eż. billi tħakkik il-ġilda, espożizzjoni għas-sħana), jipproduċu wisq istamina, li twassal għal reazzjoni allerġika li twassal għal ħorriqija lokalizzata fiż-żona ta 'irritazzjoni, xi kultant imsejjaħ "is-sinjal ta' Darier".
☆ Fir-riżultati ta' Stiftung Warentest tal-2022 mill-Ġermanja, is-sodisfazzjon tal-konsumatur b'ModelDerm kien biss ftit inqas milli b'konsultazzjonijiet bit-telemediċina mħallsa.
References
Mastocytosis hija kundizzjoni fejn hemm eċċess ta 'ċelluli mast, li spiss jinstabu f'diversi partijiet tal-ġisem bħall-ġilda, il-mudullun, u s-sistema diġestiva. Skont l-Organizzazzjoni Dinjija tas-Saħħa (WHO) , cutaneous mastocytosis jistgħu jiġu kategorizzati fi tliet tipi ewlenin. L-ewwel tip (mastocytomas) jikkonsisti f'leżjonijiet solitarji jew ftit (≤3) . It-tieni tip (urticaria pigmentosa) jinvolvi leżjonijiet multipli, tipikament ivarjaw minn aktar minn 10 sa inqas minn 100. L-aħħar tip juri involviment mifrux madwar il-ġilda. Urticaria pigmentosa hija l-aktar forma komuni ta’ mastoċitożi tal-ġilda fit-tfal, iżda tista’ sseħħ ukoll fl-adulti. Normalment tkun kundizzjoni li ma tagħmilx ħsara li ħafna drabi titjieb matul l-adolexxenza. B'differenza mastoċitożi adulti, urticaria pigmentosa rarament taffettwa l-organi interni. Karatteristika waħda distintiva ta ' urticaria pigmentosa hija t-tendenza tagħha li tikkawża tikek jew leżjonijiet żgħar, li jieħdu ħakk, kannella ħamrani, jew kannella safrani fuq il-ġilda, komunement magħrufa bħala ħorriqija. Dawn it-tikek ġeneralment jidhru fit-tfulija u jistgħu jdumu tul il-ħajja.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Tifla ta’ 6 snin daħlet b’diversi tikek ta’ kulur skur li l-ewwel dehru fuq il-qorriegħa u mbagħad infirxu ma’ wiċċha u ġisimha matul l-aħħar sitt xhur. Semmiet li tħosshom jogħlew, isiru ħomor, u ħakk meta ġiet applikata pressjoni. Hija ma esperjenzatx fwawar, rimettar, dijarea, jew tħarħir, u l-istorja medika personali u tal-familja tagħha ma pprovdewx ħjiel rilevanti. Mal-eżami, sibna bosta tikek skuri fuq il-qorriegħa, forehead, wiċċ, u għonq tagħha, flimkien ma 'irqajja' skuri kemmxejn mgħollija fuq sidirha u daharha. Il-ħakk ħafif tat-tikek wassalhom biex jintefħu u ħakk fi żmien 2 minuti, iżda s-sintomi fadu fi żmien 15-20 minuta (Darier's sign) .
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
